Phytocemical Screening and Toxicity Test of Ethanolic Extracts Phanera semibifida (Roxb.) Benth. Stem and Leaves from West Sumatra
DOI:
https://doi.org/10.55215/jber.v5i2.15Abstract
Indonesian people use plants as medicine because they are considered to have fewer side effects. Phanera semibifida (Roxb.) is a climbing plant that has been used by the community to make therapeutic drugs. Phanera semibifida, especially species in western Sumatra, lacks information on phytochemical composition and toxicity capabilities. So the purpose of this study was to determine the phytochemical content, toxicity (BSLT), and biological activity of Phanera semibifida growing in western Sumatra. The BSLT approach was used in this study to conduct phytochemical screening and toxicity studies on leaves and stems. Phytochemical results were negative for alkaloids and steroids but positive for flavonoids, tannins, saponins, and terpenoids. Based on the BSLT experiment, it can be concluded that both ethanol extracts are highly toxic and show anticancer properties
References
Aryantini, D. (2021). Aktivitas Antioksidan dan Kandungan Tanin Total Ekstrak Etanol Daun Kupu-kupu. Jurnal Farmagazine, VIII(1), 54–60.
Cahyani, Y. D., & Mita, S. R. (2018). Artikel Tinjauan: Aktivitas Biologis Tanaman Bandotan (AgeratumConyzoides Linn.) Sebagai Terapi Luka Terbuka. Jurnal Farmaka Universitas Padjajaran, 16(2), 1–9. Retrieved from https://doi.org/10.24198/jf.v16i2.17641
Dewantari, R., Lintang, M. L., & Nurmiyati. (2018). Types of Plants used as Traditional Medicines In Ex Residency of Surakarta. Bioedukasi: Jurnal Pendidikan Biologi, 11(2), 118–123. Retrieved from http://dx.doi.org/10.20961/bioedukasi-uns.v11i2.19672
Fadhli, H., Furi, M., & Jauwahir, A. (2019). Isolasi dan Uji Aktivitas Antioksidan Fraksi Alkaloid Ekstrak Metanol Kulit Batang Bunga Kupu-Kupu (Bauhinia semibifida Roxb .). Jurnal Penelitian Farmasi Indonesia, 7(2), 43–50.
Farhany, Saleh, C., & Daniel. (2024). Phytochemical Screening And Potential Biological Activity Of Bajakah (Uncaria cordata (Lour.) Merr.). Prosiding Seminar Nasional Kimia Dan Terapan III, 40–44.
Fitmawati, F., Juliantari, E., Mustika Roza, R., Titrawani, T., & Yahya, V. J. (2022). Reactualiting Phanera semibifida (Roxb.) Benth. from Sumatra, Indonesia as an Anticancer Agent and Phylogenetic Position. Pharmacognosy Reviews, 16(31), 34–39. https://doi.org/10.5530/phrev.2022.16.6
Khasanah, N. W., Karyadi, B., & Sundaryono, A. (2020). Uji Fitokimia dan Toksisitas Ekstrak Umbi Hydnophytum sp. terhadap Artemia salina Leach. PENDIPA Journal of Science Education, 4(1), 47–53. https://doi.org/10.33369/pendipa.4.1.47-53
Kumontoy, G., Deeng, D., & Mulianti, T. (2023). Pemanfaatan Tanaman Herbal Sebagai Obat Tradisional untuk Kesehatan Masyarakat di Desa Guaan Kecamatan Mooat Kabupaten Bolaang Mongondow Timur. Jurnal Holistik, 16(3), 1–20.
Makalalag AK, Sangi M, & Kumaunang M. (2019). Skrining Fitokimia dan Uji Toksisitas Ekstrak Etanol Dari Daun Turi (Sesbania grandiflora Pers). Universitas Sam Ratulangi, 38–46.
Masriana, S., Halang, B., & Mahrudin, M. (2023). Inventory of the Citrus in Barimbun Village, Tabalong District. Journal Of Biology Education Research (JBER), 4(2), 82–88. https://doi.org/10.55215/jber.v4i2.8692
Mawardi, A. L., Sarjani, T. M., & S.Pandia, E. R. (2021). Uji Potensi Antikanker Ekstrak Tiga Spesies Tanaman Sansevieria. Sainmatika: Jurnal Ilmiah Matematika Dan Ilmu Pengetahuan Alam, 18(1), 1. https://doi.org/10.31851/sainmatika.v17i3.4639
Nisa, H., Mahrudin, & Utami, N. H. (2024). Inventory of Epiphytic Ferns in Tanta Village, Tabalong District, South Kalimantan. Journal Of Biology Education Research (JBER), 5(1), 43–54.
Parinding, I. P., Hermansyah, Nurvianthi, R. Y., Aswandi, & Asmal, A. (2024). the Relationship of the Level of Knowledge of the Public About the Use of Traditional Medicine Gout in Pomgko Village, District North Walenrang. Jurnal Kesehatan Luwu Raya, 10(2), 8–16.
Praparatana, R., Maliyam, P., Barrows, L. R., & Puttarak, P. (2022). Flavonoids and Phenols, the Potential Anti-Diabetic Compounds from Bauhinia strychnifolia Craib. Stem. Molecules, 27(8), 1–16. https://doi.org/https://doi.org/10.3390/molecules27082393
Razoki, Butar-Butar, R. G., Neswita, E., Sembiring, N. B., Novriani, E., Simanjuntak, N. J. P., & Pakpahan, E. H. (2023). Uji skrining fitokimia dan pengukuran kadar total flavonoid pada ekstrak paku (Nephrolepis biserrata) dengan fraksi n-heksana, etil asetat, dan air. Journal of Pharmaceutical and Sciences, 6(3), 1142–1160. https://doi.org/10.36490/journal-jps.com.v6i3.185
Safitri, E., Zikra, Rafita, S., & Abizar. (2023). Inventory of the Orchidaceae Family in Jorong Harapan Tinggam Community Forest Talamau Pasaman Barat Distict West Sumatera. Journal Of Biology Education Research (JBER), 4(1), 17–24.
Sangi, M., Runtuwene, M. R. J., Simbala, H. E. I., & Makang, V. M. A. (2008). Analisis Fitokimia Tumbuhan Obat Di Kabupaten Minahasa Utara. Chem. Prog, 1(1), 47–53.
Saputri, D. D., & Pertiwi, M. P. (2021). Identifikasi Metabolit Sekunder dan Uji Proksimat Ekstrak Daging Keong Mas (Pomacea canaliculata L.) Identification of Secondary Metabolites and Proximate Analysis of Golden Apple Snails (Pomacea canaliculata L.) Meat Extract, 22(2), 101.
Sekhon-loodu, S., & Rupasinghe, H. P. V. (2019). Evaluation of Antioxidant , Antidiabetic and Antiobesity Potential of Selected Traditional Medicinal Plants. Frontiers in Nutrition, 6(April), 1–11. https://doi.org/10.3389/fnut.2019.00053
Setiasih, I. S., Hanidah, I.-I., Wira, D. W., Rialita, T., & Sumanti, D. M. (2016). Uji Toksisitas Kubis Bunga Diolah Minimal (KBDM) Hasil Ozonasi. Jurnal Penelitian Pangan (Indonesian Journal of Food Research), 1(1), 22–26. https://doi.org/10.24198/jp2.2016.vol1.1.04
Shahana, S., Pratima, A., & Nikalje, G. (2017). Brief Review on Bauhinia variegata: Phytochemistry, Antidiabetic and Antioxidant potential. American Journal of PharmTech Research, 7(1).
Shaikh, J. R., & Patil, M. (2020). Qualitative tests for preliminary phytochemical screening: An overview. International Journal of Chemical Studies, 8(2), 603–608. https://doi.org/https://doi.org/10.22271/chemi.2020.v8.i2i.8834
Tambunan, R. M., Rahmat, D., & Silalahi, J. S. (2016). Formulasi Tablet Nanopartikel Ekstrak Terstandar Daun Pulai (Alstonia scholaris (L). R. BR) sebagai Antidiabetes. Journal of Tropical Pharmacy and Chemistry, 3(4), 291–298. https://doi.org/10.25026/jtpc.v3i4.117
Yuruk, E., Tuken, M., Sahin, C., Kaptanagasi, A. O., Basak, K., Aykan, S., … Sarica, K. (2016). The protective effects of an herbal agent tutukon on ethylene glycol and zinc disk induced urolithiasis model in a rat model. Urolithiasis, 44(6), 501–507. https://doi.org/https://doi.org/10.1007/s00240-016-0889-2
Zakaria, Z. A., Yahya, F., Mamat, S. S., Mahmood, N. D., Mohtarrudin, N., Taher, M., … Salleh, M. Z. (2016). Hepatoprotective action of various partitions of methanol extract of Bauhinia purpurea leaves against paracetamol-induced liver toxicity: Involvement of the antioxidant mechanisms. BMC Complementary and Alternative Medicine, 16(1), 1–16. https://doi.org/10.1186/s12906-016-1110-4
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